Colorectal cancer risk in patients with inflammatory bowel disease and Lynch syndrome

نویسندگان

  • Melyssa Aronson
  • Joanne Stempak
  • Mark Silverberg
  • Kara Semotiuk
  • Robert Gryfe
  • Steven Gallinger
چکیده

Background Chronic inflammatory bowel disease (IBD) and Lynch syndrome (LS) are associated with an increased risk for developing colorectal cancer (CRC). After 8-10 years of pan-ulcerative colitis (DC), the risk of CRC is 2%, increasing by 0.5-1.0% annually. LS has been associated with a 60-80% lifetime risk of CRC. It is unclear whether individuals diagnosed with both IBD and LS would have a cumulative risk or earlier age of onset of CRC based on their diagnoses.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2010